Breast Cancer Types
ByBreast cancer type is categorized by whether it begins in the ducts or lobules, the organs responsible for breast milk production. Medullary carcinoma accounts for 15% of all breast cancer types. This breast cancer type represents 5% of all diagnosis. IPR015525 Breast cancer type 2 susceptibility protein Header EBIDatabasesInterPro Search Open in usermanual InterPro: " /> Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. The breast cancer type 2 susceptibility protein (BRCA2) is a breast tumour suppressor with a potential function in the cellular response to DNA damage. Some breast cancer types express one or more of these proteins on their cell surface, while others express none. Media Relations Contacts Online Press Kit Rumors, Myths, and Truths Glossary About the American Cancer Society Breastfeeding, Other Factors May Affect Risk of Breast Cancer TypeAtlanta 2008/08/25 -Factors such as age at menopause as well as a woman?s breastfeeding practices can influence her risk of developing certain types of breast cancer.
The investigators found that reproductive risk factors varied considerably by breast cancer subtype. Their analysis included 1,023 women with breast cancer whose cells express the estrogen and progesterone receptors (called luminal cancers), 39 women with HER2-overexpressing breast cancer, and 78 triple-negative cases (no expression of estrogen, progesterone, or HER2 receptors). The study also included 1,476 women without breast cancer. ? They added that additional studies on the causes of breast cancer subtypes are needed to better understand the biology of the disease. Learn more about our commitment to providing complete, accurate, and private breast cancer information. The study?s results suggest that there are distinct and separate hormonal risk factors associated with different subtypes of breast cancer. Women with what is referred to as "triple-negative" breast cancer are more likely than other women with breast cancer to experience a relapse, a new study by Canadian researchers shows. Despite having a high risk of early recurrence, the study indicates that triple-negative breast cancer patients who remain disease-free for eight years are unlikely to die of breast cancer and may be "cured" of their disease.
Breast Feeding Will Lowers Risk Of Breast Cancer
Breastfeeding for 6 months or longer was associated with a lower risk of luminal cancer as well as triple-negative cancer, a type that can be particularly aggressive and difficult to treat. Understanding the specific type of breast cancer can help you ask better questions and work with your physicians to get the best breast cancer treatments. For more information on the types and stages of breast cancer, watch Beyond the Shock®. Medullary carcinoma accounts for 15% of all breast cancer types. Infiltrating lobular carcinoma is a type of breast cancer that usually appears as a subtle thickening in the upper-outer quadrant of the breast. Making up about 2% of all breast cancer diagnosis, tubular carcinoma cells have a distinctive tubular structure when viewed under a microscope. Typically this type of breast cancer is found in women aged 50 and above. Inflammatory breast cancer is a rare and very aggressive type of breast cancer that causes the lymph vessels in the skin of the breast to become blocked.
Breast Cancer Risk
The study’s results suggest that there are distinct and separate hormonal risk factors associated with different subtypes of breast cancer. Amanda Phipps, a predoctoral research associate at the Fred Hutchinson Cancer Research Center in Seattle, and her colleagues conducted a study to better understand the specific risk factors for the subtypes of breast cancer, which are classified by expression of the estrogen receptor, the progesterone receptor, and the HER2 receptor. The investigators found that reproductive risk factors varied considerably by breast cancer subtype. Breastfeeding for 6 months or longer was associated with a lower risk of luminal cancer as well as triple-negative cancer, a type that can be particularly aggressive and difficult to treat. Both late age at menopause and use of estrogen plus progestin hormone therapy were associated with an increased risk of luminal disease. Finally, no differences in risks associated with number of children or the age when a woman first gave birth were observed by subtype. The study authors concluded that their results indicate that "certain reproductive factors may have a greater impact on risk of certain molecular subtypes of disease compared to others. Despite having a high risk of early recurrence, the study indicates that triple-negative breast cancer patients who remain disease-free for eight years are unlikely to die of breast cancer and may be "cured" of their disease. Insulin resistance, hyperinsulinemia, and changes in the signaling of growth hormones and steroid hormones associated with diabetes may affect the risk of breast cancer. Despite many proposed potential pathways, the mechanisms underlying an association between diabetes and breast cancer risk remain unclear, particularly because the 2 diseases share several risk factors, including obesity, a sedentary lifestyle, and possibly intake of saturated fat and refined carbohydrates, that may confound this association. Although the metabolic syndrome is closely related to diabetes and embraces additional components that might influence breast cancer risk, the role of the metabolic syndrome in breast carcinogenesis has not been studied and thus remains unknown.
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Question and Answer
CANCER??????????????????????????????????????????????????
went to a specialist after months of severe neck pain…and on the Mri it showed a white lump on my neck. The dr didn't seem concerned and had me have a ct scan. He said it was a benign hemangioma and nothing to worry about. This lump has been killing me, feeling like it was twisting my neck, last night I was up till 7:30 am. I also developed chest pain..and pain in my left side, could that be the spleen? I don't know what the problem is, and the dr's don't have a clue either…any ideas? Could this be cancer? Aren't malignant tumors not painful and benign ones painful? If it isn't cancer…then what?? I had lyme disease last year but was treated…is it possible I wasn't on medication long enough? The tick bite has gotten red again…from last year?? Or is this just a coincidence?
I also have severe burning on my left side, by the ribs..and what I assume is the spleen looks enlarged. I have joint pain, and my back burns so much that I thought I had a heating pad on lol…my mom said that means inflamation of the kidneys??? Is this cancer? Lyme disease? IDK
I had lyme disease last year, but was treated. I have joint pain,and the bite where the tick bit turns red on occasional days, but that was last year? I have had some headaches and hearing loss…LYME DISEASE?
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15 Comments
March 25th, 2010 at 11:32 pm
Inflamatory breast cancer is most likely:
"Although most breast cancers begin as lumps or tumors, inflammatory breast cancer usually starts with a feeling of thickness or heaviness in the breast."
"Inflammatory breast cancer (IBC) is a rare and aggressive form of breast cancer. According to the National Cancer Institute, about 1-5% of all breast cancer cases in the United States are inflammatory breast cancers."
Otherwise, try Invasive Lobular Carcinoma,
"In other cases, the first sign of ILC is a thickening or hardening in the breast that can be felt, rather than a distinct lump."
"About 10% of all invasive breast cancers are invasive lobular carcinomas. "
March 26th, 2010 at 12:19 am
A pink ribbon was used by Estee Lauder of the cosmetic company to support breast cancer research. Estee Lauder had breast cancer and wanted a way to raise public awareness. She took the idea from another woman who was using a peach colored ribbon to raise public awareness . . the two had a disagreement about whether to involve businesses in raising money for breast cancer research. Estee Lauder used her business clout to convince many companies to support 'pink' for cancer research . . she is the one behind all the pink merchandising and its promotion.
So pink ribbons and pink are used almost exclusively for breast cancer.
Prior to pink ribbons the idea to use a ribbon to support a need came from the AIDS epidemic when entertainers began to wear a red ribbon to support those people dying from AIDS. Later when Desert Storm came along people began to tie a yellow ribbon around trees from the song "Tie a yellow ribbon round the old oak tree if you still want me".
Since the red ribbon for AIDS, the yellow ribbon for US troops, and pink ribbons for breast cancer . . other diseases and causes have been adopting colors and ribbons to raise public awareness too.
List of awareness ribbons
http://en.wikipedia.org/wiki/List_of_awareness_ribbons
Not every cancer has an 'official' ribbon or color. The organizations for different cancers sometimes adopt a ribbon, but nothing is 'official' about them . . so sometimes you will see a green ribbon for leukemia and sometimes an orange ribbon or sometimes both together.
Here is another list:
http://www.personalizedcause.com/shop/collections/classic/causes/ab.html
It is best to buy ribbons directly from the organization you wish to support so that you know they receive the 'donation'.
March 26th, 2010 at 12:36 am
Answer:
ER-Negative and PR-Negative Breast Cancers.
Immunohistochemistry lab testing procedures of breast cancer tumors for certain features (such as estrogen receptor assays, progesterone receptors assays, and HER-2/neu) is a major step in deciding which type of breast cancer are receptive or not receptive to estrogen and progesterone (hormones) within our body. For doctors knowing this this allows them more leverage in decision making as to what is best for your particular cancer situation.
Aside from HER-2/neu which is a type of receptor protein that helps cells to grow in cancer in a more agressive fashion, the two hormones in women of most concern is estrogen and progesterone. These two hormones stimulate the growth of normal breast cells and play a major role in many breast cancer treatment options. Cancer cells tend to respond to these hormones through the estrogen receptors (ER) and progesterone receptors (PR).
ER and PR are a cells welcoming mat for these hormones circulating throughout the bloodstream. Cancer tumors are tested for these receptors in a test called a hormone receptor assay. If a cancer does not have these receptors, it is referred to as hormone receptor negative (estrogen-receptor negative and progesterone-receptor negative). If the cancer has these receptors, it is referred to as hormone receptor positive (ER-receptor positive and/or PR-receptor positive) or just ER-positive or PR-positive.
Positive or negative receptor hormones within breast lesions is what matters here. The hormone receptors are important because cancer cells that are ER or PR-positive often stop growing if the woman takes drugs that either block the effect of estrogen and progesterone or decrease the body's levels of estrogen. these drugs lower the chance that the cancer will come back or recur and also improve the chances of the patient living longer. Most women with ER-positive or PR-positive cancer will take these drugs as part of their chemotherapy treatment protocol. However, these hormones-active drugs are not effective if your cancer does not contain these receptors.
March 25th, 2010 at 11:15 pm
woulda been funny if the dirt flew in his face lmao
March 26th, 2010 at 12:34 am
The BBC use buly boy balliffs to ensure they get their money from single parent mothers who simply cannot afford the hundreds of pounds they’re being asked for, often seizing goods from families with very liitle, in order to pay grossly inflated wage packets. Well done BBC.
March 26th, 2010 at 7:42 am
SECOND^^
March 26th, 2010 at 2:56 pm
You can read all about the types here
http://www.breastbiopsy.com/bioresults_typesofbreastcancer.jsp
March 26th, 2010 at 11:21 am
its only been up for like 20 minutes, besides it has about 200 now that I’m watching.
March 26th, 2010 at 1:32 pm
FIRST
March 27th, 2010 at 7:20 pm
the pink ribbon with a saying that says EARLY DETECTION SAVES LIVE-es you can star early detection once a month at home__a picture of a family that says YES u have alot to life for
March 27th, 2010 at 11:16 pm
I agree with you. The Komen foundation is very, very well organized and spends about a quarter-billion dollars a year funding cancer research specifically for breast cancer. This represents probably around one-half of one percent of all cancer funding. The remaining 99.5% of cancer funding comes from national governments, especially the US government, and the pharmaceutical sector. Though it is a small portion of overall funding it is a very impressive sum for a grass-roots organization and it has most certainly raised breast cancer awareness. I don't think any of us have ever seen anything like the Komen.
I wish there were some way to raise awareness without turning every teenage girl into a breast cancer hypochondriac, and I wish the formidable resources and organization of the Komen would branch out and focus on other cancers as well. In truth, many of the treatments developed to fight cancer will work on several different types, including breast cancer. Breast cancer remains a big problem in the world, but so do colon, lung, and ovarian, and prostate cancers. If you are unlucky enough to develop a cancer that is rare and not well studied there are few options for you. The big money, almost all the money, is going into the Top 5 cancers, including breast cancer.
March 28th, 2010 at 4:31 am
Sounds like a homework question to me. The only way to learn is to do your own homework, but I’ll give you a start.
Basically there are two categories, invasive and non-invasive. Then you have various histology’s:
About 80% of all breast cancers are ductal carcinomas, about 10% are lobular, about 1% are inflammatory (the most dangerous) and the rest are various types; papillary, tubular, mucinous, etc, etc., etc.
Tumors can be both invasive and non-invasive and they can be a combination of histologys.
March 28th, 2010 at 5:21 am
They recommend these as preventative screening measures. They do not test for ovarian cancer it is cervical cancer which they screen for. As well as colon cancer. They test for these because early detection is key in all cancer. These are only the select few that can be detected without invasive surgery or expensive testing.
Ovarian Cancer is not tested for as a preventative measure, but it should be for it is only the matter of an internal exam and a CA-125 test which cost about $100 to run verses $500 for an internal ultrasound.
They test for these to help prevent cancer and save lives.
March 28th, 2010 at 6:53 pm
mammary carcinoma
mammary= breast
carcinoma= cancerous tumor
March 28th, 2010 at 12:49 pm
Yeah cuz your friend’s video has been up for 5 minutes.
XD